Lions Mane as a Nootropic

Increasing amounts of studies indicate Lions mane mushroom (Hericium erinaceus) to be highly beneficial for brain and nerve health and function.

There are two main active compounds found within Lions mane mushrooms which are associated with its nootropic qualities:

The fruiting body of Lions mane contains Hericenones and its mycelium contains Erinacines.

Lions Mane Mushroom has a nootropic effect on the brain

Hericenones and erinacines have a low molecular weight which enables it to pass through the blood-brain barrier to stimulate the production of Nerve Growth Factor (NGF).

The role of NGF is to simulate growth, repair and protection of nerves and neurons. As we get older synthesis of NGF declines which is thought to be a contributor to age-related decline in cognition, memory, and recall.

Like Hericenones the Erinacines found within the mycelium of Lions mane show remarkably similar effects on NGF production. In fact, one lead researcher into the use of Lions mane for prevention of dementia and Alzheimer’s states:

“Erinacines are the most powerful inducers of NGF synthesis among all currently identified natural compounds”

Dr Hirokazu Kawagishi

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